In the 1980s Andy Warhol created a series of paintings based around Leonardo da Vinci’s The Last Supper. The one above is currently on view at The Warhol Museum in Pittsburgh, Pennsylvania.

In 2010 it was on view as part of the Brooklyn Museum’s exhibition Andy Warhol: The Last Decade.

From their website about the work-

The Last Supper series was commissioned to inaugurate a new gallery in Milan, Italy, located across the street from the site of the Italian Renaissance artist Leonardo da Vinci’s iconic fresco (circa 1495–98) depicting Jesus’s last meal with his followers. Warhol worked obsessively for more than a year on this series, producing more than a hundred Last Supper paintings, both silkscreened and hand-painted, that were some of the largest paintings of his career.

Despite his public proclamations to the contrary, Warhol was profoundly moved by the series. Of these works, he remarked, “I painted them all by hand—I myself; so now I’ve become a Sunday painter. . . . That’s why the project took so long. But I worked with a passion.” These paintings manifest both his religious beliefs—his practice of Catholicism remained private until it was revealed at his funeral—and an irreverence toward the subject, expressed through ironic commercial logos and transgressive repetitions of Christ’s image.

Warhol created many variations using versions and pieces of da Vinci’s fresco and there is some debate as to the meanings behind them. In 2018, curator Jessica Beck wrote Warhol’s Confession: Love, Faith, and AIDs, an in-depth essay exploring possible meanings behind the work. She suggests Warhol was referencing AIDS, suffering, health, and mortality, along with his relationship to Christianity.

In this section of the essay she discusses the imagery from the painting-

The tension between Warhol’s sexuality and his religious life has its fullest expression in paintings such as The Last Supper (The Big C), in which signs and symbols create a private reference to AIDS. Hand-painted via a projection process, like paintings of 1961–62 such as Before and After, Wigs, and Dr. Scholl’s Corns, the canvas is left partly unfinished, and Warhol employs a light touch with an abstract brushstroke. On this canvas the figure of Christ recurs four times, while hands appear repeatedly. Thomas’s finger pointing to the sky, intimating that heaven knows he is free of guilt, appears prominently next to the “eye” in the Wise potato-chip logo.

…The source material for the painting, in the archives of The Andy Warhol Museum, Pittsburgh, is a collage made up of headlines from the New York Post, motorcycle ads, and clippings reading “the Big C” and “AIDS” cut from a front-page article in the Post. Warhol ultimately left out the AIDS headline while keeping the more covert “The Big C,” but given the direct references to “gay cancer” in his diaries, it becomes clear that this image of Christ was connected for him to the rapid rate at which people were dying around him. “The Big C” was synonymous with AIDS. The Last Supper (The Big C) reflects on sex and shame through appropriated images of Christ’s betrayal, the piercing owl’s eye (the Wise logo), and the numbers 699, appropriated from a price tag—$6.99—but indexing both the sexual position “69” and the “mark of the beast,” 666, in the Book of Revelations. Even the details of Christ’s feet at the far right of the canvas seem to point to the notion of punishment: for Steinberg, writing on Leonardo’s Last Supper, “as [Christ’s feet] rejoin the rest of the body, they foreshadow it glorified; and they foreshadow it crucified.”34  The image of Christ offering his flesh in the Eucharist was a symbol of salvation during a time of suffering, an unusually personal and emotional image for Warhol. In keeping with the complexities of his construction of death in the Death and Disasters, and with its repression in the diaries, the painting speaks of sex and of judgment. It is an allegorical triangulation of mourning, punishment, and fear.

For more on Warhol an his diaries, the Netflix documentary is really informative as well as entertaining. It’s a moving portrait that goes beyond what most people know about Warhol, both as an artist and as a person.